Looking treatment complications in the mouth.

نویسنده

  • Norra MacReady
چکیده

(Scott noted that they didn’t invent these concepts. “These are all things that have been studied by different people over the last 30 or 40 years.”) According to Scott, developing a mathematical model will help define both the concentration of CTCs and their phenotypic distribution at any given point in the network, as well as organ-specific filtration values. “We recognize that each of these biological processes is probably diseaseand even patient-specific,” he said. To parameterize this model, Scott said, researchers will need to characterize and count CTCs taken from one patient at different times and from different points in this network. A complete understanding of the model will also yield information about the behavior of the system as a whole, Scott continued. Specifically, researchers will be able to calculate the average lifespan of a CTC in a patient’s circulation with minimal measurements. “Although this seems to be a simple calculation, the scientific literature on this topic is substantially conflicted, with reports of cells lasting on the order of years in some patients but less than 24 hours in others,” said Scott. The researchers wrote that even this seemingly simple factor will differ between patients and cancer types and will lead to many questions:

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عنوان ژورنال:
  • Journal of the National Cancer Institute

دوره 105 2  شماره 

صفحات  -

تاریخ انتشار 2013